Basic Information

Gene symbol MME Synonyms CALLA, CD10, CMT2T, NEP, SCA43, SFE Type of gene protein-coding
Description membrane metalloendopeptidase

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

Gene symbol CD38 Synonyms ADPRC 1, ADPRC1, cADPR1 Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description CD38 molecule

Gene symbol CRLF2 Synonyms CRL2, CRLF2Y, TSLPR Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description cytokine receptor like factor 2

GTO ID GTC2145
Trial ID NCT04016129
Disease B-Cell Acute Lymphoblastic Leukemia
Altered gene CD22|CD123|CD38|CD10|CD20|TSLPR
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR-T cells
Generation4th
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleCAR-T Immunotherapy Targeting CD19- ALL
Year2019
CountryChina
Company sponsorShenzhen Geno-Immune Medical Institute
Other ID(s)GIMI-IRB-19003

Clinical Result

Cohort 1
Administration route None
Pts 100
Age Child, Adult, Older_Adult

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