Gene symbol | MME | Synonyms | CALLA, CD10, CMT2T, NEP, SCA43, SFE | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q25.2 | dbXrefs | |
Description | membrane metalloendopeptidase |
Gene symbol | IL3RA | Synonyms | CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra | Type of gene | protein-coding |
Chromosome | X|Y | Map location | X;Y | dbXrefs | |
Description | interleukin 3 receptor subunit alpha |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Description | membrane spanning 4-domains A1 |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
Gene symbol | CD38 | Synonyms | ADPRC 1, ADPRC1, cADPR1 | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4p15.32 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | CD38 molecule |
Gene symbol | CRLF2 | Synonyms | CRL2, CRLF2Y, TSLPR | Type of gene | protein-coding |
Chromosome | X|Y | Map location | X;Y | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | cytokine receptor like factor 2 |
GTO ID | GTC2145 |
Trial ID | NCT04016129 |
Disease | B-Cell Acute Lymphoblastic Leukemia |
Altered gene | CD22|CD123|CD38|CD10|CD20|TSLPR |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CAR-T cells |
Generation | 4th |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | CAR-T Immunotherapy Targeting CD19- ALL |
Year | 2019 |
Country | China |
Company sponsor | Shenzhen Geno-Immune Medical Institute |
Other ID(s) | GIMI-IRB-19003 |
Cohort 1 | |||||||
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