Basic Information

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

Gene symbol COLEC10 Synonyms 3MC3, CL-10, CL-34, CLL1 Type of gene protein-coding
Description collectin subfamily member 10

GTO ID GTC2139
Trial ID NCT04010877
Disease Acute Myeloid Leukemia
Altered gene CLL1|CD33|CD123
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD123/CD33/CLL1 CAR-T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleMultiple CAR-T Cell Therapy Targeting AML
Year2019
CountryChina
Company sponsorShenzhen Geno-Immune Medical Institute
Other ID(s)GIMI-IRB-19004
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 10
Age Child, Adult, Older_Adult

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