Gene symbol | IL3RA | Synonyms | CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra | Type of gene | protein-coding | |
Chromosome | X|Y | Map location | X;Y | dbXrefs | Entrez:3563 MIM:308385 MIM:430000 HGNC:HGNC:6012 Ensembl:ENSG00000185291 Ensembl:ENSG00000292332 AllianceGenome:HGNC:6012 | |
Description | interleukin 3 receptor subunit alpha |
Gene symbol | CD33 | Synonyms | CD33rSiglec, SIGLEC-3, SIGLEC3, p67 | Type of gene | protein-coding | |
Chromosome | 19 | Map location | 19q13.41 | dbXrefs | Entrez:945 MIM:159590 HGNC:HGNC:1659 Ensembl:ENSG00000105383 AllianceGenome:HGNC:1659 | |
Gene perturbation-related omics dataset | PerturbAtlas | |||||
Description | CD33 molecule |
Gene symbol | COLEC10 | Synonyms | 3MC3, CL-10, CL-34, CLL1 | Type of gene | protein-coding | |
Chromosome | 8 | Map location | 8q24.12 | dbXrefs | Entrez:10584 MIM:607620 HGNC:HGNC:2220 Ensembl:ENSG00000184374 AllianceGenome:HGNC:2220 | |
Description | collectin subfamily member 10 |
GTO ID | GTC2139 |
Trial ID | NCT04010877 |
Disease | Acute Myeloid Leukemia |
Altered gene | CLL1|CD33|CD123 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD123/CD33/CLL1 CAR-T cells |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | Multiple CAR-T Cell Therapy Targeting AML |
Year | 2019 |
Country | China |
Company sponsor | Shenzhen Geno-Immune Medical Institute |
Other ID(s) | GIMI-IRB-19004 |
Vector information | |||
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Cohort 1 | |||||||
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