Basic Information

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC2131
Trial ID NCT03999697
Disease B-Cell Lymphoma | Follicular Lymphoma | Extranodal Marginal Zone Lymphoma of Mucosa-Associated Lymphoid Tissue | Plasma Cell Neoplasm | Mantle Cell Lymphoma | Diffuse Large B-Cell Lymphoma
Altered gene CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD22 CAR-T cells
PhasePhase1
Recruitment statusUnknown
TitleA Clinical Research of CD22-Targeted CAR-T in B Cell Malignancies
Year2018
CountryChina
Company sponsorPersonGen BioTherapeutics (Suzhou) Co., Ltd.
Other ID(s)PG-CART-22-I-001

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 10
Age Child, Adult, Older_Adult
Lymph depletion Yes

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