Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2126
Trial ID NCT03984968
Disease B-Cell Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Co-treatment feeding T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleCD19 CAR-T Consolidation Therapy for Acute Lymphoblastic Leukemia
Year2019
CountryChina
Company sponsorThe First Affiliated Hospital of Soochow University
Other ID(s)SZCART01

Clinical Result

Cohort 1
Administration route None
Pts 13
Age Adult
Outcome 13/13(CR). The relapse-free survival was 84%, and the overall survival was 83% with a median follow-up of 27 months.
Adverse reactions 13/13(cytopenia); 12/13(hypogammaglobinemia)
References PMID: 36897251

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