Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
GTO ID | GTC2116 |
Trial ID | NCT03954106 |
Disease | Neurotoxicity Syndromes | Diffuse Large B-Cell Lymphoma |
Altered gene | CD19 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | YesCAR-Ta|Axicabtagene Ciloleucel|axi-cel |
Co-treatment | defibrotide |
Generation | 2nd |
Phase | Phase2 |
Recruitment status | Terminated |
Title | A Safety and Efficacy Study of Defibrotide in the Prevention of Chimeric Antigen Receptor-T-cell-associated Neurotoxicity |
Year | 2019 |
Country | United States |
Company sponsor | Jazz Pharmaceuticals |
Other ID(s) | JZP395-201 |
Vector information | |||||
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