Basic Information


GTO ID GTC2112
Trial ID NCT03946800
Disease Cancer
Altered gene IL-12
Therapeutic/Target gene Therapeutic gene
TherapymRNA
Treatment MEDI1191
Co-treatment Durvalumab
PhasePhase1
Recruitment statusCompleted
TitleA Phase 1, Open-label, Dose-escalation and Expansion Study of MEDI1191 Administered Intratumorally as Monotherapy and in Combination With Durvalumab in Subjects With Advanced Solid Tumors
Year2019
CountryUnited States|Spain
Company sponsorMedImmune LLC
Other ID(s)D8510C00001|2020-005784-31
Vector information
Vectorlipid nanoparticle

Clinical Result

Cohort 1
Administration route intravenous injection
Dosage MEDI1191, at least twice|Durvalumab, every 4 weeks
Pts 61
Age Adult, Older_Adult

Relationship Graph

Overview of Knowledge Graph