Basic Information

Gene symbol TNFRSF10B Synonyms CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 Type of gene protein-coding
Description TNF receptor superfamily member 10b

Gene symbol EGFR Synonyms ERBB, ERBB1, ERRP, HER1, NISBD2, PIG61, mENA Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description epidermal growth factor receptor


Gene symbol CTAG1B Synonyms CTAG, ESO1, CT6.1, CTAG1, LAGE-2, LAGE2B, NY-ESO-1 Type of gene protein-coding
Description cancer/testis antigen 1B

GTO ID GTC2108
Trial ID NCT03941626
Disease Stomach Cancer | Liver Cancer | Esophageal Cancer | Brain Glioma
Altered gene EGFR|DR5|NY-ESO-1|MESO
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR-T cells
PhasePhase1|Phase2
Recruitment statusUnknown
TitleAutologous CAR-T/TCR-T Cell Immunotherapy for Solid Malignancies
Year2019
CountryChina
Company sponsorShenzhen BinDeBio Ltd.
Other ID(s)2019BDB016

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 50
Age Adult, Older_Adult
Lymph depletion Yes

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