Basic Information

Gene symbol LMP2 Synonyms None Type of gene protein-coding
Description EBNA3A nuclear protein

GTO ID GTC2096
Trial ID NCT03925896
Disease Nasopharyngeal Disease
Altered gene EBV-LMP2
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment LMP2 TCR-T cells
HLAHLA-A*02|HLA-A*11|HLA-A*24
PhasePhase1
Recruitment statusUnknown
TitleLMP2 Antigen-specific High-affinity T Cell Receptor (TCR)-Transduced Autologous T-cell Therapy for Recurrent and Metastatic Nasopharyngeal Carcinoma, an Open-label, Single-center, Phase I Clinical Trial
Year2019
CountryChina
Company sponsorSun Yat-sen University
Other ID(s)B2019-021

Clinical Result

Cohort 1
Administration route infusion
Dosage 0.5~5E7 cells
Donor type autologous
Age Adult, Older_Adult
Lymph depletion No

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