Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC2095
Trial ID NCT03919526
Disease Acute Lymphoblastic Leukemia
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleAnti-CD19/CD22 Bispecific CAR-T Cell Therapy for MRD Positive ALL
Year2019
CountryChina
Company sponsorShanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Other ID(s)SHSYXY-CAR-T MRD+ALL
Vector information
Vectorretrovirus

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 18
Age Adult, Older_Adult

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