Basic Information

Gene symbol E7 Synonyms None Type of gene protein-coding
Description transforming protein E7

GTO ID GTC2089
Trial ID NCT03912831
Disease Cancer
Altered gene E7
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment KITE-439
HLAHLA-A*02:01
PhasePhase1
Recruitment statusTerminated
TitleA Phase 1 Study Evaluating the Safety and Efficacy of HPV16 E7 T Cell Receptor Engineered T Cells (KITE-439) in HLA-A*02:01+ Subjects With Relapsed/Refractory HPV16+ Cancers
Year2019
CountryUnited States
Company sponsorKite, A Gilead Company
Other ID(s)KT-US-478-0401|2020-005455-20

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Age Adult, Older_Adult
Lymph depletion Yes

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