Basic Information

Gene symbol CLDN18 Synonyms SFTA5, SFTPJ Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description claudin 18

GTO ID GTC2079
Trial ID NCT03890198
Disease Pancreatic Ductal Adenocarcinoma | Stomach Cancer
Altered gene CLDN18
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment LCAR-C182A cells
PhaseEarly_Phase1
Recruitment statusTerminated
TitleA Phase 1 Study of LCAR-C182A Cells in the Treatment of Advanced Gastric Cancer and Pancreatic Ductal Adenocarcinoma
Year2019
CountryChina
Company sponsorFirst Affiliated Hospital Xi'an Jiaotong University
Other ID(s)MO-GPC01

Clinical Result

Cohort 1
Administration route None
Pts 2
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph