Gene symbol | AFP | Synonyms | AFPD, FETA, HPAFP | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4q13.3 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | alpha fetoprotein |
GTO ID | GTC2078 |
Trial ID | NCT03888859 |
Disease | Metastatic Liver Cancer | Hepatocellular Carcinoma | Liver Cancer |
Altered gene | AFP |
Therapeutic/Target gene | Therapeutic gene |
Therapy | Gene transfer |
Treatment | ET1402L1-ARTEMIS T cells |
HLA | HLA-A*02 |
Phase | Phase1 |
Recruitment status | Completed |
Title | Phase 1, Open-label, Three Routes IV, Intratumoral Injections and Intra-hepatic Artery Dose-escalation Clinical Study to Evaluate the Safety and Efficacy of ET1402L1-ARTEMIS2 T- Cells in AFP Expressing Hepatocellular Carcinoma (HCC) |
Year | 2019 |
Country | China |
Company sponsor | First Affiliated Hospital Xi'an Jiaotong University |
Other ID(s) | XJTU1AF2017LSL-C002 |
Vector information | |||
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Cohort 1 | |||||||||
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