Basic Information

Gene symbol AFP Synonyms AFPD, FETA, HPAFP Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description alpha fetoprotein

GTO ID GTC2078
Trial ID NCT03888859
Disease Metastatic Liver Cancer | Hepatocellular Carcinoma | Liver Cancer
Altered gene AFP
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment ET1402L1-ARTEMIS T cells
HLAHLA-A*02
PhasePhase1
Recruitment statusCompleted
TitlePhase 1, Open-label, Three Routes IV, Intratumoral Injections and Intra-hepatic Artery Dose-escalation Clinical Study to Evaluate the Safety and Efficacy of ET1402L1-ARTEMIS2 T- Cells in AFP Expressing Hepatocellular Carcinoma (HCC)
Year2019
CountryChina
Company sponsorFirst Affiliated Hospital Xi'an Jiaotong University
Other ID(s)XJTU1AF2017LSL-C002
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route injection
Donor type autologous
Age Adult, Older_Adult
Lymph depletion No

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