Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC2074
Trial ID NCT03881761
Disease B-Cell Lymphoma
Altered gene CD19|CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD20 CAR-T cells
PhasePhase1
Recruitment statusUnknown
TitleCD19/20 Bispecific Nanobody-derived CAR-T Cells in B Cell Lymphoma
Year2019
CountryChina
Company sponsorHenan Cancer Hospital
Other ID(s)HenanCH CART 2-3

Clinical Result

Cohort 1
Administration route None
Dosage 1~3E6 cells/kg
Pts 50
Age Child, Adult, Older_Adult
Lymph depletion Yes

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