Basic Information

Gene symbol IFNA2 Synonyms IFN-alpha-2, IFN-alphaA, IFNA, IFNA2B, leIF A Type of gene protein-coding
Description interferon alpha 2

GTO ID GTC2070
Trial ID NCT03875495
Disease Multiple Myeloma
Altered gene IFNA2
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment Temferon
PhasePhase1|Phase2
Recruitment statusTerminated
TitleA Phase I/II Dose Escalation Study Evaluating Safety and Activity of Autologous CD34+-Enriched Hematopoietic Progenitor Cells Genetically Modified With a Lentiviral Vector Encoding for the Human Interferon-ɑ2 Gene in Multiple Myeloma Patients With Early Relapse After Intensive Front Line Therapy
Year2019
CountryItaly
Company sponsorGenenta Science
Other ID(s)TEM-MM-101
Vector information
Vectorlentivirus
Transgene/Inserted genehuman interferon-alpha 2 gene

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type autologous
Pts 9
Age Adult, Older_Adult

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