Basic Information

Gene symbol IFNA2 Synonyms IFN-alpha-2, IFN-alphaA, IFNA, IFNA2B, leIF A Type of gene protein-coding
Description interferon alpha 2

GTO ID GTC2067
Trial ID NCT03866109
Disease Glioblastoma Multiforme
Altered gene IFNA2
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment Temferon
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleA Phase I/IIa Dose Escalation Study Evaluating the Safety and Efficacy of Autologous CD34+-Enriched HSPCs Genetically Modified With Human Interferon-α2 in Patients With Glioblastoma Multiforme and Unmethylated MGMT Gene Promoter
Year2019
CountryItaly
Company sponsorGenenta Science
Other ID(s)TEM-GBM_001|2018-001404-11
Vector information
Vectorlentivirus
Transgene/Inserted genehuman interferon-alpha 2 gene

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type autologous
Pts 27
Age Adult, Older_Adult

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