Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC2055
Trial ID NCT03824964
Disease B-Cell Lymphoma
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment CD19/CD22 CAR-NK cells
PhaseEarly_Phase1
Recruitment statusUnknown
TitleStudy of Anti-CD19/CD22 CAR NK Cells in Relapsed and Refractory B Cell Lymphoma
Year2019
CountryChina
Company sponsorAllife Medical Science and Technology Co., Ltd.
Other ID(s)CD19/CD22 CAR NK-BJZL-01

Clinical Result

Cohort 1
Administration route None
Dosage 5~60E4 cells/kg
Pts 10
Age Adult, Older_Adult
Lymph depletion Yes

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