Basic Information

Gene symbol GSTP1 Synonyms DFN7, FAEES3, GST3, GSTP, HEL-S-22, PI Type of gene protein-coding
Description glutathione S-transferase pi 1

GTO ID GTC2053
Trial ID NCT03819387
Disease Colorectal Cancer | Lung Non-Small Cell Carcinoma | Pancreatic Cancer
Altered gene GSTP
Therapeutic/Target gene Target gene
TherapysiRNA
Treatment NBF-006
PhasePhase1
Recruitment statusActive, Not Recruiting
TitleA Phase I/Ib Open-Label, Multi-Center, Dose-Escalation Study to Investigate the Safety, Pharmacokinetics and Preliminary Efficacy of Intravenous NBF 006 in Patients With Non-Small Cell Lung, Pancreatic, or Colorectal Cancer Followed by a Dose Expansion Study in Patients With KRAS-Mutated Non-Small Cell Lung Cancer
Year2019
CountryUnited States
Company sponsorNitto BioPharma, Inc.
Other ID(s)NBF-006-001
Vector information
Vectorlipid nanoparticle

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage NBF-006, once-weekly x 4 consecutive weeks, every 6 weeks
Pts 44
Age Adult, Older_Adult

Relationship Graph

Overview of Knowledge Graph