Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol SDC1 Synonyms CD138, SDC, SYND1, syndecan Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description syndecan 1

Gene symbol CD38 Synonyms ADPRC 1, ADPRC1, cADPR1 Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description CD38 molecule

Gene symbol CSH1 Synonyms CS-1, CSA, CSMT, GHB3, PL, hCS-1, hCS-A Type of gene protein-coding
Description chorionic somatomammotropin hormone 1

Gene symbol ITGB7 Synonyms None Type of gene protein-coding
Description integrin subunit beta 7

GTO ID GTC2035
Trial ID NCT03778346
Disease Multiple Myeloma
Altered gene ITGB7|BCMA|CS1|CD38|CD138
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR-T cells
Generation4th
PhasePhase1
Recruitment statusUnknown
TitleIntegrin β7, BCMA, CS1, CD38 and CD138 as the Single or Compound Targets for the Fourth Genenation of CAR-T Cells
Year2018
CountryChina
Company sponsorThe Sixth Affiliated Hospital of Wenzhou Medical University
Other ID(s)SixthAHWenzhouMU

Clinical Result

Cohort 1
Administration route None
Pts 30
Age Adult, Older_Adult

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