Gene symbol | HBB | Synonyms | CD113t-C, ECYT6, beta-globin | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11p15.4 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | hemoglobin subunit beta |
GTO ID | GTC2008 |
Trial ID | NCT03728322 |
Disease | Thalassemia |
Altered gene | HBB |
Therapeutic/Target gene | Target gene |
Therapy | Gene editing |
Treatment | HBB gene corrected iHSCs |
Phase | Early_Phase1 |
Recruitment status | Unknown |
Title | A Safety and Efficacy Study of a Single Center, Open-label, Single Arm About the Gene Correction of HBB in Patient-specific iHSCs Using CRISPR/Cas9 That Intervent Subjests With β-thalassemia Mutations |
Year | 2018 |
Country | China |
Company sponsor | Allife Medical Science and Technology Co., Ltd. |
Other ID(s) | HBB HSC-01 |
Cohort 1 | |||||||
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