Basic Information

Gene symbol EGFR Synonyms ERBB, ERRP, HER1, mENA, ERBB1, PIG61, NISBD2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description epidermal growth factor receptor

GTO ID GTC2006
Trial ID NCT03726515
Disease Glioblastoma
Altered gene EGFR
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment EGFRvIII CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusCompleted
TitleCART-EGFRvIII + Pembrolizumab in GBM
Year2019
CountryUnited States
Company sponsorUniversity of Pennsylvania
Other ID(s)831706, UPCC 13318

Clinical Result

Cohort 1
Administration route None
Pts 7
Age Adult, Older_Adult

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