Basic Information


GTO ID GTC2004
Trial ID NCT03721068
Disease Neuroblastoma | Osteosarcoma
Altered gene GD2
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment GD2 CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitleStudy of CAR T-Cells Targeting the GD2 With IL-15+iCaspase9 for Relapsed/Refractory Neuroblastoma or Relapsed/Refractory Osteosarcoma
Year2019
CountryUnited States
Company sponsorUNC Lineberger Comprehensive Cancer Center
Other ID(s)LCCC 1743-ATL

Clinical Result

Cohort 1
Administration route None
Dosage 0.5E6 cells/kg, 1E6 cells/kg, 1.5E6 cells/kg
Pts 18
Age Child, Adult, Older_Adult
Lymph depletion Yes

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