Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1991
Trial ID NCT03696784
Disease B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Co-treatment Bendamustine
PhasePhase1
Recruitment statusRecruiting
TitleAnti-CD19 CAR-T Cells With Inducible Caspase 9 Safety Switch for B-cell Lymphoma
Year2019
CountryUnited States
Company sponsorUNC Lineberger Comprehensive Cancer Center
Other ID(s)LCCC 1813-ATL
Vector information
Vectorretrovirus

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 2E6 cells/kg
Donor type Autologous
Pts 30
Age Adult, Older_Adult
Lymph depletion Yes

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