| Gene symbol | ERBB2 | Synonyms | CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) | Type of gene | protein-coding |
| Chromosome | 17 | Map location | 17q12 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | erb-b2 receptor tyrosine kinase 2 | ||||
| GTO ID | GTC1990 |
| Trial ID | NCT03696030 |
| Disease | HER2-Receptor Positive Breast Cancer | Leptomeninges Sarcoma | Breast Cancer | Malignant Neoplasm | Brain Neoplasm |
| Altered gene | HER2 |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | HER2 CAR-T cells |
| Phase | Phase1 |
| Recruitment status | Recruiting |
| Title | HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases |
| Year | 2018 |
| Country | United States |
| Company sponsor | City of Hope Medical Center |
| Other ID(s) | 17237|NCI-2018-01270|17237 |
| Cohort 1 | |||||||
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