Basic Information

Gene symbol LAMP3 Synonyms CD208, DC LAMP, DC-LAMP, DCLAMP, LAMP, LAMP-3, TSC403 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description lysosomal associated membrane protein 3

Gene symbol UL83 Synonyms None Type of gene protein-coding
Description tegument protein pp65

GTO ID GTC1982
Trial ID NCT03688178
Disease Glioblastoma
Altered gene UL83|LAMP
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
Treatment Human CMV pp65-LAMP mRNA-pulsed autologous DCs
Co-treatment Temozolomide|Unpulsed DCs
PhasePhase2
Recruitment statusActive, Not Recruiting
TitleDC Migration Study to Evaluate TReg Depletion In GBM Patients With and Without Varlilumab
Year2020
CountryUnited States
Company sponsorAnnick Desjardins, MD
Other ID(s)Pro00082570
Vector information
Vectordendritic cell

Clinical Result

Cohort1: Unpulsed DCs
Administration route intradermal injection
Dosage 2E7 cells, every 2 weeks and all subsequent vaccines (up to 10) occur monthly
Pts 43
Age Adult, Older_Adult
Cohort2: Td
Administration route intradermal injection
Dosage 2E7 cells, every 2 weeks and all subsequent vaccines (up to 10) occur monthly
Pts 43
Age Adult, Older_Adult
Cohort3: Varlilumab_Td
Administration route intradermal injection
Dosage 2E7 cells, every 2 weeks and all subsequent vaccines (up to 10) occur monthly
Pts 43
Age Adult, Older_Adult

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