Gene symbol | PRAME | Synonyms | CT130, MAPE, OIP-4, OIP4 | Type of gene | protein-coding |
Chromosome | 22 | Map location | 22q11.22 | dbXrefs | |
Description | PRAME nuclear receptor transcriptional regulator |
GTO ID | GTC1981 |
Trial ID | NCT03686124 |
Disease | Solid Tumor |
Altered gene | PRAME |
Therapeutic/Target gene | Target gene |
Therapy | TCR-T cell |
Treatment | IMA203;IMA203CD8 |
HLA | HLA phenotype positive |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | Phase 1 Study Evaluating Genetically Modified Autologous T Cells Expressing a TCR Recognizing a Cancer/Germline Antigen as Monotherapy or in Combination With Nivolumab in Patients With Recurrent and/or Refractory Solid Tumors |
Year | 2018 |
Country | United States|Germany |
Company sponsor | Immatics US, Inc. |
Other ID(s) | IMA203-101 |
Cohort1: IMA203/IMA203CD8 | |||||||||
|
|||||||||
Cohort2: IMA203/IMA203CD8_Nivolumab | |||||||||
|