Basic Information

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

GTO ID GTC1974
Trial ID NCT03672851
Disease Acute Leukemia | Acute Myeloid Leukemia
Altered gene CD123
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD123 CAR-T cells
PhasePhase1
Recruitment statusTerminated
TitleStudy Evaluating Safety and Efficacy of CAR-T Cells Targeting CD123 in Patients With Acute Leukemia
Year2019
CountryChina
Company sponsorSecond Affiliated Hospital of Xi'an Jiaotong University
Other ID(s)anti-CD123 CAR-T therapy

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.5E6~2E6 cells/kg
Donor type Autologous
Pts 2
Age Child, Adult, Older_Adult
Lymph depletion Yes

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