Basic Information

Gene symbol SDC1 Synonyms CD138, SDC, SYND1, syndecan Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description syndecan 1

GTO ID GTC1973
Trial ID NCT03672318
Disease Multiple Myeloma
Altered gene CD138
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR138 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleStudy of ATLCAR.CD138 Cells for Relapsed/Refractory Multiple Myeloma
Year2019
CountryUnited States
Company sponsorUNC Lineberger Comprehensive Cancer Center
Other ID(s)LCCC 1603-ATL

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 5E6 cells/kg, 1E7 cells/kg, 2.5E7 cells/kg, 5E7 cells/m^2, 1E8 cells/m^2, 2E8 cells/m^2
Donor type Autologous
Pts 33
Age Adult, Older_Adult
Lymph depletion Yes

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