Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC1966
Trial ID NCT03661554
Disease Multiple Myeloma
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BCMA CAR-T cells
Generation2nd
PhaseEarly_Phase1
Recruitment statusUnknown
TitleBCMA Nano Antibody CAR-T Cells for Patients With Refractory and Relapsed Multiple Myeloma
Year2018
CountryChina
Company sponsorThe Pregene (ShenZhen) Biotechnology Company, Ltd.
Other ID(s)PRG 1801
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route None
Dosage 5E6 cells/kg, 7.5E6 cells/kg, 1.5E7 cells kg
Pts 15
Age Adult, Older_Adult

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