Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC1965
Trial ID NCT03651128
Disease Multiple Myeloma
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment Abecma|bb2121|BMS-986395|Idecabtagene vicleucel|ide-cel
Location approved US, Canada, EU, UK, Japan, Israel, Switzerland
PhasePhase3
Recruitment statusActive, Not Recruiting
TitleEfficacy and Safety Study of bb2121 Versus Standard Regimens in Subjects With Relapsed and Refractory Multiple Myeloma (RRMM)
Year2018
CountryUnited States
Company sponsorCelgene
Other ID(s)BB2121-MM-003|U1111-1217-9988|2018-001023-38

Clinical Result

Cohort 1
Administration route None
Dosage 150~450E6 cells
Donor type Autologous
Pts 381
Age Adult, Older_Adult
Lymph depletion Yes

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