Basic Information

Gene symbol PMEL Synonyms D12S53E, HMB-45, HMB45, ME20, ME20-M, ME20M, P1, P100, PMEL17, SI, SIL, SILV, gp100 Type of gene protein-coding
Description premelanosome protein

GTO ID GTC1964
Trial ID NCT03649529
Disease Malignant Adenoma
Altered gene gp100
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment GPA-TriMAR-T
Generation2nd
PhaseEarly_Phase1
Recruitment statusUnknown
TitleTreatment of Malignant Melanoma With GPA-TriMAR-T Cell Therapy
Year2018
CountryChina
Company sponsorTimmune Biotech Inc.
Other ID(s)T2018-7
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route None
Donor type Autologous
Pts 6
Age Adult, Older_Adult

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