Basic Information

Gene symbol LMP-1 Synonyms None Type of gene protein-coding
Description latent membrane protein LMP-1

Gene symbol LMP2 Synonyms None Type of gene protein-coding
Description EBNA3A nuclear protein

GTO ID GTC1963
Trial ID NCT03648697
Disease Nasopharyngeal Disease
Altered gene EBV-LMP1|EBV-LMP2
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment YT-E001
HLAHLA-A*02:01|HLA-A*24:02|HLA-A*11:01
PhasePhase2
Recruitment statusUnknown
TitleA Pilot Study of EBV-TCR-T(YT-E001) in NPC Patients
Year2018
CountryChina
Company sponsorFujian Cancer Hospital
Other ID(s)HXYT-001
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route infusion
Dosage 2E8 cells
Donor type autologous
Age Adult, Older_Adult
Lymph depletion Yes

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