Gene symbol | TNFRSF17 | Synonyms | BCM, BCMA, CD269, TNFRSF13A | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p13.13 | dbXrefs | |
Description | TNF receptor superfamily member 17 |
Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
Gene symbol | CD33 | Synonyms | CD33rSiglec, SIGLEC-3, SIGLEC3, p67 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.41 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | CD33 molecule |
Gene symbol | CD38 | Synonyms | ADPRC 1, ADPRC1, cADPR1 | Type of gene | protein-coding |
Chromosome | 4 | Map location | 4p15.32 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | CD38 molecule |
Gene symbol | MET | Synonyms | AUTS9, DA11, DFNB97, HGFR, RCCP2, c-Met | Type of gene | protein-coding |
Chromosome | 7 | Map location | 7q31.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | MET proto-oncogene, receptor tyrosine kinase |
Gene symbol | TNFRSF10B | Synonyms | CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 | Type of gene | protein-coding |
Chromosome | 8 | Map location | 8p21.3 | dbXrefs | |
Description | TNF receptor superfamily member 10b |
Gene symbol | EGFR | Synonyms | ERBB, ERBB1, ERRP, HER1, NISBD2, PIG61, mENA | Type of gene | protein-coding |
Chromosome | 7 | Map location | 7p11.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | epidermal growth factor receptor |
Gene symbol | CTAG1B | Synonyms | CTAG, ESO1, CT6.1, CTAG1, LAGE-2, LAGE2B, NY-ESO-1 | Type of gene | protein-coding |
Chromosome | X | Map location | Xq28 | dbXrefs | |
Description | cancer/testis antigen 1B |
GTO ID | GTC1957 |
Trial ID | NCT03638206 |
Disease | B-Cell Acute Lymphoblastic Leukemia | Myeloid Leukemia | Pancreatic Cancer | Multiple Myeloma | Liver Cancer | Stomach Cancer | Renal Carcinoma | Mesothelioma | Synovial Sarcoma | Colorectal Cancer | Melanoma | Brain Glioma | Ovarian Cancer | Lung Cancer | Lymphoma | Esophageal Cancer |
Altered gene | CD19|CD22|CD33|BCMA|CD38|NY-ESO-1|DR5|c-MET|EGFR|MESO |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CAR-T cells |
Phase | Phase1|Phase2 |
Recruitment status | Unknown |
Title | Autologous CAR-T/TCR-T Cell Immunotherapy for Malignancies |
Year | 2018 |
Country | China |
Company sponsor | Shenzhen BinDeBio Ltd. |
Other ID(s) | 2018ZDYFY-BinDeDBD |
Cohort 1 | |||||||||
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