Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

Gene symbol CD38 Synonyms ADPRC 1, ADPRC1, cADPR1 Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description CD38 molecule

Gene symbol MET Synonyms AUTS9, DA11, DFNB97, HGFR, RCCP2, c-Met Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description MET proto-oncogene, receptor tyrosine kinase

Gene symbol TNFRSF10B Synonyms CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9 Type of gene protein-coding
Description TNF receptor superfamily member 10b

Gene symbol EGFR Synonyms ERBB, ERBB1, ERRP, HER1, NISBD2, PIG61, mENA Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description epidermal growth factor receptor


Gene symbol CTAG1B Synonyms CTAG, ESO1, CT6.1, CTAG1, LAGE-2, LAGE2B, NY-ESO-1 Type of gene protein-coding
Description cancer/testis antigen 1B

GTO ID GTC1957
Trial ID NCT03638206
Disease B-Cell Acute Lymphoblastic Leukemia | Myeloid Leukemia | Pancreatic Cancer | Multiple Myeloma | Liver Cancer | Stomach Cancer | Renal Carcinoma | Mesothelioma | Synovial Sarcoma | Colorectal Cancer | Melanoma | Brain Glioma | Ovarian Cancer | Lung Cancer | Lymphoma | Esophageal Cancer
Altered gene CD19|CD22|CD33|BCMA|CD38|NY-ESO-1|DR5|c-MET|EGFR|MESO
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR-T cells
PhasePhase1|Phase2
Recruitment statusUnknown
TitleAutologous CAR-T/TCR-T Cell Immunotherapy for Malignancies
Year2018
CountryChina
Company sponsorShenzhen BinDeBio Ltd.
Other ID(s)2018ZDYFY-BinDeDBD

Clinical Result

Cohort 1
Administration route infusion
Donor type Autologous
Pts 73
Age Child, Adult, Older_Adult

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