| Gene symbol | EGFR | Synonyms | ERBB, ERBB1, ERRP, HER1, NISBD2, PIG61, mENA | Type of gene | protein-coding |
| Chromosome | 7 | Map location | 7p11.2 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
| Description | epidermal growth factor receptor | ||||
| GTO ID | GTC1955 |
| Trial ID | NCT03638167 |
| Disease | Atypical Teratoid Rhabdoid Tumor | Brain Ependymoma | Pediatric Central Nervous System Tumor | Germ Cell Tumor | Medulloblastoma | Primitive Neuroectodermal Tumor | Choroid Plexus Carcinoma | Brain Glioma | Pineoblastoma |
| Altered gene | EGFR |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | EGFR806 CAR-T cells |
| Phase | Phase1 |
| Recruitment status | Active, Not Recruiting |
| Title | EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors |
| Year | 2019 |
| Country | United States |
| Company sponsor | Seattle Children's Hospital |
| Other ID(s) | BrainChild-02 |
| Vector information | |||
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| Cohort1: Tumor Cavity Infusion | |||||||
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| Cohort2: Ventricular System Infusion | |||||||
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