Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC1948
Trial ID NCT03628612
Disease Acute Lymphoblastic Leukemia | Diffuse Large B-Cell Lymphoma | Multiple Myeloma | T-Cell Lymphoma
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment AUTO-LT1
PhasePhase2
Recruitment statusRecruiting
TitleLong-term Follow-up of Patients Treated With Autologous T Cells Genetically Modified
Year2018
CountryUnited Kingdom
Company sponsorAutolus Limited
Other ID(s)AUTO-LT1
Vector information
Vectorretrovirus

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 500
Age Child, Adult, Older_Adult

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