Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1947
Trial ID NCT03628053
Disease Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment Kymriah|Tisagenlecleucel
Generation2nd
PhasePhase3
Recruitment statusWithdrawn
TitleTisagenlecleucel vs Blinatumomab or Inotuzumab for Patients With Relapsed/Refractory B-cell Precursor Acute Lymphoblastic Leukemia
Year2018
CountrySwitzerland
Company sponsorNovartis Pharmaceuticals
Other ID(s)CCTL019I2301
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 0
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph