Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
GTO ID | GTC1945 |
Trial ID | NCT03620058 |
Disease | Acute Lymphoblastic Leukemia |
Altered gene | CD19|CD22 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CAR-T22-65s|CD19 CAR-T cells |
Generation | 2nd |
Phase | Phase1 |
Recruitment status | Active, Not Recruiting |
Title | CART22 Alone or in Combination With huCART19 for ALL |
Year | 2018 |
Country | United States |
Company sponsor | University of Pennsylvania |
Other ID(s) | IRB # 830049; UPCC #12418 |
Vector information | |||||
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Cohort1: CD22 | |||||||||
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Cohort2: CD22+CD19 | |||||||||
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