Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | EGFR | Synonyms | ERBB, ERBB1, ERRP, HER1, NISBD2, PIG61, mENA | Type of gene | protein-coding |
Chromosome | 7 | Map location | 7p11.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | epidermal growth factor receptor |
GTO ID | GTC1943 |
Trial ID | NCT03618381 |
Disease | Sarcoma | Germ Cell Tumor |
Altered gene | EGFR|CD19 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | EGFR806 CAR-T cells|CD19 CAR-T cell |
Generation | 2nd |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults |
Year | 2018 |
Country | United States |
Company sponsor | Seattle Children's Hospital |
Other ID(s) | STRIvE-01 |
Vector information | |||||
|
Cohort1: EGFR | |||||||||
|
|||||||||
Cohort2: EGFR+CD19 | |||||||||
|