Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding | |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | Entrez:930 MIM:107265 HGNC:HGNC:1633 Ensembl:ENSG00000177455 AllianceGenome:HGNC:1633 | |
Description | CD19 molecule |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding | |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | Entrez:931 MIM:112210 HGNC:HGNC:7315 Ensembl:ENSG00000156738 AllianceGenome:HGNC:7315 | |
Description | membrane spanning 4-domains A1 |
GTO ID | GTC1938 |
Trial ID | NCT03605238 |
Disease | Neuromyelitis Optica |
Altered gene | CD19|CD20 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD19/CD20 CAR-T cells |
Generation | 2nd |
Phase | Phase1 |
Recruitment status | Withdrawn |
Title | Treatment of Relapsed and/or Refractory AQP4-IgG Seropositive NMOSD by Tandem CAR T Cells Targeting CD19 and CD20 |
Year | 2018 |
Country | China |
Company sponsor | Chinese PLA General Hospital |
Other ID(s) | CHN-PLAGH-NO-S2018-002-02 |
Vector information | |||||
|
Cohort 1 | |||||||||||
|