Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1931
Trial ID NCT03598179
Disease B-Cell Lymphoma | Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment XLCAR-T001
PhasePhase2
Recruitment statusUnknown
TitleXLCART001 Treatment in Relapsed/Refractory/High-risk B-cell Malignancy Subjects
Year2018
CountryChina
Company sponsorThe First Affiliated Hospital with Nanjing Medical University
Other ID(s)JSPH-CART001
Vector information
Vectorlentivirus

Clinical Result

Cohort1: dose level 1
Administration route None
Dosage 4E6 cells/kg
Age Adult, Older_Adult
Cohort2: dose level 2
Administration route None
Dosage 2E6 cells/kg
Age Adult, Older_Adult
Cohort3: dose level 3
Administration route None
Dosage 1E7 cells/kg
Age Adult, Older_Adult

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