Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1928
Trial ID NCT03594162
Disease Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
Recruitment statusNo Longer Available
TitleCompassionate Use of CAR T Cells Targeting the CD19 Antigen and Containing the Inducible Caspase 9 Safety Switch
Year2018
CountryUnited States
Company sponsorUNC Lineberger Comprehensive Cancer Center
Other ID(s)LCCC 1830-ATL-COM
Vector information
Vectorretrovirus

Clinical Result

Cohort 1
Administration route None
Dosage 5E5 cells/kg, 1E5 cells/kg
Age Child, Adult, Older_Adult
Lymph depletion Yes

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