Basic Information

Gene symbol CCR5 Synonyms CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description C-C motif chemokine receptor 5

GTO ID GTC1926
Trial ID NCT03593187
Disease HIV Infection
Altered gene CCR5
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment Cal-1
PhasePhase1|Phase2
Recruitment statusCompleted
TitleA Phase I/II Study of the Safety of CD34+ Haematopoietic Stem/Progenitor Cells and CD4+ T Lymphocytes Transduced With LVsh5/C46, a Dual Anti-HIV Gene Transfer Construct, in HIV-1 Infected Patients With High-risk Lymphoma
Year2018
CountryFrance
Company sponsorAssistance Publique - Hôpitaux de Paris
Other ID(s)P 141004|2015-004453-41
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route None
Donor type autologous
Pts 2
Age Adult

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