Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC1925
Trial ID NCT03593109
Disease B-Cell Lymphoma
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhasePhase1
Recruitment statusTerminated
TitleA Single-center Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of LCAR-L10D Cell Formulations Targeting CD19 and CD22 in Patients With CD19- and/or CD22-Positive Relapsed/Refractory B-cell Lymphoma
Year2019
CountryChina
Company sponsorSecond Affiliated Hospital of Xi'an Jiaotong University
Other ID(s)Legend-CART-201803-Ⅱ

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.5E6 cells/kg, 1.5E6 cells/kg, 5E6 cells/kg
Pts 1
Age Adult, Older_Adult

Relationship Graph

Overview of Knowledge Graph