Basic Information

Gene symbol FOSL1 Synonyms FRA, FRA1, fra-1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description FOS like 1, AP-1 transcription factor subunit

GTO ID GTC1923
Trial ID NCT03585764
Disease Fallopian Tube Cancer | Peritoneal Carcinoma | Ovarian Cancer
Altered gene FRa
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment MOv19-BBz CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitlePhase I Clinical Trial of Adoptive Transfer of Autologous Folate Receptor - Alpha Redirected T Cells for Recurrent High Grade Serous Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
Year2018
CountryUnited States
Company sponsorUniversity of Pennsylvania
Other ID(s)830111 (UPCC-03818)

Clinical Result

Cohort 1
Administration route None
Pts 18
Age Adult, Older_Adult
References : 431 First-in-human phase I clinical trial evaluating intraperitoneal administration of MOv19-BBz CAR T cells in patients with alpha folate receptor-expressing recurrent high grade serous ovarian cancer

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