Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC1913
Trial ID NCT03573700
Disease Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment SJCAR19|CD19 CAR-T cells
Co-treatment Mesna
Generation2nd
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleEvaluation of CD19-Specific CAR Engineered Autologous T-Cells for Treatment of Relapsed/Refractory CD19+ Acute Lymphoblastic Leukemia
Year2018
CountryUnited States
Company sponsorSt. Jude Children's Research Hospital
Other ID(s)SJCAR19|NCI-2017-01399
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 35
Age Child, Adult
Lymph depletion Yes

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