Basic Information

Gene symbol BIRC5 Synonyms API4, EPR-1 Type of gene protein-coding
Description baculoviral IAP repeat containing 5

Gene symbol TERT Synonyms CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description telomerase reverse transcriptase

GTO ID GTC1903
Trial ID NCT03548571
Disease Glioblastoma
Altered gene BIRC5|TERT
Therapeutic/Target gene Therapeutic gene
TherapymRNA vaccine
Co-treatment temozolomide
PhasePhase2|Phase3
Recruitment statusActive, Not Recruiting
TitleOpen Label Randomized Phase II/III Trial of Dendritic Cell Immunotherapy Against Cancer Stem Cells in Glioblastoma Patients Receiving Standard Therapy (DEN-STEM)
Year2018
CountryNorway
Company sponsorOslo University Hospital
Other ID(s)DEN-STEM
Vector information
Vectordendritic cell

Clinical Result

Cohort1: IMP
Administration route intradermal injection
Age Adult, Older_Adult
References PMID: 32691060
Cohort2: Standard therapy
Administration route None
Age Adult, Older_Adult
References PMID: 32691060

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