Gene symbol | BIRC5 | Synonyms | API4, EPR-1 | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q25.3 | dbXrefs | |
Description | baculoviral IAP repeat containing 5 |
Gene symbol | TERT | Synonyms | CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT | Type of gene | protein-coding |
Chromosome | 5 | Map location | 5p15.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | telomerase reverse transcriptase |
GTO ID | GTC1903 |
Trial ID | NCT03548571 |
Disease | Glioblastoma |
Altered gene | BIRC5|TERT |
Therapeutic/Target gene | Therapeutic gene |
Therapy | mRNA vaccine |
Co-treatment | temozolomide |
Phase | Phase2|Phase3 |
Recruitment status | Active, Not Recruiting |
Title | Open Label Randomized Phase II/III Trial of Dendritic Cell Immunotherapy Against Cancer Stem Cells in Glioblastoma Patients Receiving Standard Therapy (DEN-STEM) |
Year | 2018 |
Country | Norway |
Company sponsor | Oslo University Hospital |
Other ID(s) | DEN-STEM |
Vector information | |||
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Cohort1: IMP | |||||||
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Cohort2: Standard therapy | |||||||
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