Gene symbol | TP53 | Synonyms | BCC7, BMFS5, LFS1, P53, TRP53 | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17p13.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | tumor protein p53 |
GTO ID | GTC1900 |
Trial ID | NCT03544723 |
Disease | Head and Neck Squamous Cell Carcinoma |
Altered gene | P53 |
Therapeutic/Target gene | Therapeutic gene |
Therapy | Gene transfer |
Treatment | AdV-p53 |
Phase | Phase2 |
Recruitment status | Unknown |
Title | A Phase 2, Multi-Center, Open Label Study to Evaluate Adenoviral p53 (Ad-p53) in Combination With Immune Checkpoint Inhibitor Therapy in Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma and Other Tumors Approved for Anti-PD-1 or Anti-PD-L1 Therapy |
Year | 2018 |
Country | United States |
Company sponsor | MultiVir, Inc. |
Other ID(s) | Ad-p53-002 |
Vector information | |||||||||
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Cohort 1 | |||||||
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