Gene symbol | IL12A | Synonyms | CLMF, IL-12A, NFSK, NKSF1, P35 | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q25.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | interleukin 12A |
Gene symbol | IL12B | Synonyms | CLMF, CLMF2, IL-12B, IMD28, IMD29, NKSF, NKSF2 | Type of gene | protein-coding |
Chromosome | 5 | Map location | 5q33.3 | dbXrefs | |
Description | interleukin 12B |
Gene symbol | FOLH1 | Synonyms | FGCP, FOLH, GCP2, GCPII, NAALAD1, PSM, PSMA, mGCP | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11p11.12 | dbXrefs | |
Description | folate hydrolase 1 |
Gene symbol | TERT | Synonyms | CMM9, DKCA2, DKCB4, EST2, PFBMFT1, TCS1, TP2, TRT, hEST2, hTRT | Type of gene | protein-coding |
Chromosome | 5 | Map location | 5p15.33 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | telomerase reverse transcriptase |
Gene symbol | WT1 | Synonyms | AWT1, GUD, NPHS4, WAGR, WIT-2, WT-1, WT33 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11p13 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | WT1 transcription factor |
GTO ID | GTC1880 |
Trial ID | NCT03491683 |
Disease | Glioblastoma |
Altered gene | WT1|PSMA|TERT|IL-12A|IL-12B |
Therapeutic/Target gene | Therapeutic gene |
Therapy | Gene transfer |
Treatment | INO-5401|INO-9012 |
Co-treatment | Cemiplimab|Radiation Therapy|Temozolomide |
Phase | Phase1|Phase2 |
Recruitment status | Active, Not Recruiting |
Title | An Open-Label, Multi-Center Trial of INO-5401 and INO-9012 Delivered by Electroporation (EP) in Combination With REGN2810 in Subjects With Newly-Diagnosed Glioblastoma (GBM) |
Year | 2018 |
Country | United States |
Company sponsor | Inovio Pharmaceuticals |
Other ID(s) | GBM-001 |
Vector information | |||
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Cohort 1 | |||||||
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