Basic Information

Gene symbol KIT Synonyms C-Kit, CD117, MASTC, PBT, SCFR Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description KIT proto-oncogene, receptor tyrosine kinase

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

Gene symbol PROM1 Synonyms AC133, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description prominin 1

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

Gene symbol CD34 Synonyms None Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD34 molecule

Gene symbol CD38 Synonyms ADPRC 1, ADPRC1, cADPR1 Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description CD38 molecule

Gene symbol NCAM1 Synonyms CD56, MSK39, NCAM Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description neural cell adhesion molecule 1

Gene symbol MUC1 Synonyms ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description mucin 1, cell surface associated

GTO ID GTC1874
Trial ID NCT03473457
Disease Acute Myeloid Leukemia
Altered gene CD33|CD38|CD56|CD117|CD123|CD133|CD34|MUC1
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR-T cells
Recruitment statusTerminated
TitleCAR-T Cells Therapy in Relapsed/Refractory Acute Myeloid Leukemia
Year2018
CountryChina
Company sponsorZhujiang Hospital
Other ID(s)2017-XYNK-002

Clinical Result

Cohort 1
Administration route None
Dosage 1E6~E7 cells/kg
Pts 2
Age Child, Adult, Older_Adult

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