Basic Information

Gene symbol TGFB2 Synonyms G-TSF, LDS4, TGF-beta2 Type of gene protein-coding
Description transforming growth factor beta 2

GTO ID GTC1862
Trial ID NCT03431311
Disease Colorectal Cancer
Altered gene TGFB2
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment TGFbetaII TCR-T cells
HLAHLA-A*02
PhasePhase1|Phase2
Recruitment statusTerminated
TitleProtocol for Treatment Under Hospital Exemption: T Cell Receptor Based Therapy of Metastatic Colorectal Cancer With mRNA-engineered T Cells Targeting Transforming Growth Factor Beta Receptor Type II (TGFβII)
Year2018
CountryNorway
Company sponsorOslo University Hospital
Other ID(s)TCR-CRC-001

Clinical Result

Cohort 1
Administration route infusion
Age Adult, Older_Adult
Lymph depletion No

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