Basic Information

Gene symbol CSF2 Synonyms CSF, GMCSF Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description colony stimulating factor 2

GTO ID GTC1861
Trial ID NCT03430687
Disease Bladder Urothelial Carcinoma
Altered gene GMCSF
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment Talimogene Laherparepvec|Imlygic|T-VEC|JS1 34.5-hGMCSF 47- pA-
PhasePhase1
Recruitment statusWithdrawn
TitleA Phase I Study of Intravesical Talimogene Laherparepvec for Non-Muscle Invasive Transitional Cell Carcinoma
Year2018
CountryUnited States
Company sponsorUniversity of California, San Francisco
Other ID(s)15521|NCI-2018-00109|15-17558|15521
Vector information
Vectorherpes simplex virus

Clinical Result

Cohort 1
Administration route intravesical injection
Dosage 1E6 PFU/10mL on days 1, 8, 15, 22, 29, and 36 or days 1, 15, and 29 in the absence of disease progression or unacceptable toxicity
Pts 0
Age Adult, Older_Adult

Relationship Graph

Overview of Knowledge Graph